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HIV drug resistance : ウィキペディア英語版 | HIV drug resistance
HIV drug resistance occurs when microevolution causes virions to become tolerant to antiretroviral treatments. ==Limited effects of current drugs (outdated) == HIV develops resistance when it evades the effects of these treatments.〔Freeman, S., and J. C. Herron. 2007. Evolutionary Analysis. 4th ed. A case for evolutionary thinking: understanding HIV. Pearson Benjamin Cummings, San Francisco, CA.〕 A recent study estimated the percentage of the American HIV positive population with some form of drug resistance to be 76.3%.〔Richman, D. D., S. C. Morton, T. Wrin, N. Hellmann, S. Berry, M. F. Shapiro, and S. A. Bozzette. 2004. The prevalence of antiretroviral drug resistance in the United States. AIDS. 18: 1393–1401.〕 Certain intrinsic features of HIV facilitate its widespread resistance, most importantly its extremely high mutation rate.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「HIV drug resistance」の詳細全文を読む
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